Termination in E.coli (Prokaryotes)
DNA Replication overview
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Termination- Basics...
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Terminator sequences...
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Tus Protein...
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Final Steps of termination... (Topoisomerase II!)
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DNA Polymerase immobilised in replication factories
- Experimental evidence favours that DNA polymerases are immobilsed rather than tracking along DNA
- Thought to be attached to the cell membrane in prokaryotes and nuclear matrix in eukaryotic cells.
- All proteins required in process are recruted to fixed location (replication factories)
- DNA fed through factory
Reference
1) Lecture notes
2) Books
1) Lecture notes
2) Books
- Lehninger, Biochemistry, 5th ed
- http://www.fastbleep.com/biology-notes/31/171/976